hrp0089p1-p138 | Fetal, Neonatal Endocrinology and Metabolism P1 | ESPE2018

Measurement of Estradiol and Testosterone in Umbilical Cord Blood by Gas Chromatography-Tandem Mass Spectrometry (GC-MS/MS); Comparisons with Radioimmunoassay (RIA)

Allvin Kerstin , Dahlgren Jovanna , Andersson Mats X , Ankarberg-Lindgren Carina

Background: We have previously shown radioimmunoassay (RIA) and gas chromatography-tandem mass spectrometry (GC-MS/MS) to be comparable when analyzing estradiol and testosterone concentrations in prepubertal and pubertal children. However, the reliability for steroid hormone determination with RIA in umbilical cord blood is not known. In general, older studies using RIA show higher values of testosterone, than more recent ones using MS/MS.Patients and me...

hrp0082p3-d1-884 | Perinatal and Neonatal Endocrinology | ESPE2014

Gender Differences in Sex Steroids and IGF1 at Birth and at 5 Years of Age

Allvin Kerstin , Karlsson Ann-Katrine , Ankarberg-Lindgren Carina , Dahlgren Jovanna

Background: Gender differences in sex steroids and IGF1 are well known from pubertal years into adulthood. Few studies report data from pre-school years.Objective and hypotheses: To study gender specific changes in sex steroids and IGF1 at birth and at 5 years of age and correlate these with auxological measurements. There are gender differences in IGF1 levels due to differences in sex steroids already at birth and during pre-school years.<p class="a...